Amyotrophic lateral sclerosis (ALS) is a here neurodegenerative disease characterized by accumulation of fragmented insoluble TDP-43 and loss of TDP-43 from the nucleus.Increased expression of exogenous TARDBP (encoding TDP-43) induces TDP-43 pathology and cytotoxicity, suggesting the involvement of aberrant expression of TDP-43 in the pathogenesis
[Purpose/Significance] A fleshlight automatique large number of image resources in digital humanities have not been in effective use for a long time, and the phenomenon of "isolated image islands" is intensifying.The International Image Interoperability Framework (IIIF) opens a new window for more in-depth interactions with image applications.Image
In order to solve the problem that digging lotus roots manually was high in labor intensity, low in efficiency and easy to damage lotus roots, and, in view of the defects of the high cost of existing digging lotus roots equipment and the cumbersome operating process needing a certain experience in technology, a jetting spin type digging lotus root
Time-dependent dielectric breakdown (TDDB) is one of the most important reliability issues in Cu/low-k technology development.With continuous technology scalings to nanometer scales, TDDB issue is further exacerbated.In this paper, two failure mechanisms were investigated: the Ta ions migration model and the line-edge-roughness (LER) model, which i